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Journal Information

Online ISSN
1305-3124

Established
1993

Editors-in-Chief
​Cihat Şen, ​Nicola Volpe

Editors
Daniel Rolnik, Mar Gil, Murat Yayla, Oluş Api

Statistics Editor
Resul Arısoy

Article info

Edward syndrome: a case report. Perinatal Journal 2014;22(3):SE12 DOI: 10.2399/prn.14.S001084

Author(s) Information

Sevcan Arzu Arınkan,
Resul Arısoy,
Emre Erdoğdu,
Oya Demirci,
Oya Pekin,
Mesut Polat,
Murat Muhçu

  1. S.B. Zeynep Kamil Kadın ve Çocuk Hastalıkları Eğitim ve Araştırma Hastanesi, Perinatoloji Kliniği- İstanbul TR
Correspondence

Murat Muhçu, S.B. Zeynep Kamil Kadın ve Çocuk Hastalıkları Eğitim ve Araştırma Hastanesi, Perinatoloji Kliniği- İstanbul TR,

Publication History
Conflicts of Interest

No conflicts declared.

Objective 
Edward syndrome, is the second common autosomal trisomy and most of the cases are lost during their first year of life because of severe cardiac pathologies. We aimed to present a case of Edward Syndrome which is prenatally diagnosed and to discuss the management in these cases.
Case 
A 35-year-old gravida 2, para 1 patient was referred to our clinic at 17 weeks gestation. A detailed ultrasound scan was revealed that alobar holoprosencephaly, proboscis, hypotelorism, polydactyly and midfacial cleft palate-lip. Parents were informed about the fetal prognosis and termination of pregnancy was put forward as an option. Karyotype analysis was performed.
Conclusion 
Edward Syndrome can include holoprosencephaly and midfacial defects. Karyotype analysis should be performed and termination of pregnancy should be offered as an option for these cases.
Keywords

Edward Syndrome, Trisomy 18, Prenatal diagnosis

File/Dsecription
Figure 1
Edward Syndrome- Polydactyly
Figure 2
Edward Syndrome- Facial Defects,Proboscis
Figure 3
Edward Syndrome-Holoprosencephaly