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Journal Information

Online ISSN
1305-3124

Established
1993

Editors-in-Chief
​Cihat Şen, ​Nicola Volpe

Editors
Daniel Rolnik, Mar Gil, Murat Yayla, Oluş Api

Statistics Editor
Resul Arısoy

Double notches: association of uterine artery notch forms with maternal outcome

İbrahim Polat, Ali Gedikbasi, Huseyin Kiyak, Bekir Gulac, Alev Atis, Gokhan Goynumer, Oznur Dundar, Cemal Ark

Article info

Double notches: association of uterine artery notch forms with maternal outcome. Perinatal Journal 2014;22(3):SE23 DOI: 10.2399/prn.14.S001084

Author(s) Information

İbrahim Polat1,
Ali Gedikbasi1,
Huseyin Kiyak1,
Bekir Gulac1,
Alev Atis1,
Gokhan Goynumer2,
Oznur Dundar1,
Cemal Ark1

  1. İstanbul Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi- İstanbul TR
  2. İstanbul Medeniyet Üniversitesi, Göztepe Eğitim ve Araştırma Hastanesi- İstanbul TR
Correspondence

Ali Gedikbasi, İstanbul Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi- İstanbul TR,

Publication History
Conflicts of Interest

No conflicts declared.

Objective
To assess uterine artery Doppler waveforms and notches performed in the third trimester as a predictor of adverse outcomes.
Methods 
Of 490 pre-eclampsia patients between 24 and 34 weeks gestation, 166 were diagnosed with mild pre-eclampsia and 324 were diagnosed with severe pre-eclampsia. Patients with complete data were divided into four groups as patients with no notch (n:58), a unilateral notch (n:93), bilateral notches (n:252) and double notches (n:39).
Results 
Bilateral and double notches were predictive of shorter follow-up times, adverse laboratory outcomes (mean 24 h proteinuria, AST, LDH levels) and HELLP syndrome, need for magnesium sulphate treatment, higher systolic and diastolic blood pressure (Table 1 and 2).
Conclusion 
Bilateral notches and especially double notches represent progressive deterioration in the uterine artery and are predictive of adverse maternal outcomes.
Keywords

Pre-eclampsia, double notches, maternal outcome

File/Dsecription
Table 1
Dunn’s multiple comparison test for uterine artery between groups Group 1: Patients without notch; Group 2: Patients with unilateral notch; Group 3: Patients with bilateral notches; Group 4: Patients with double notches
Table 2
Maternal outcome related with uterine artery waveform (n: 442)