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Journal Information

Online ISSN
1305-3124

Established
1993

Editors-in-Chief
​Cihat Şen, ​Nicola Volpe

Editors
Daniel Rolnik, Mar Gil, Murat Yayla, Oluş Api

Statistics Editor
Resul Arısoy

Successful first trimester intrauterine treatment with alcohol in a case of acardiac twin pregnancy

Melih Atahan Güven , Harika Bodur Öztürk, Önder Koç, Serkan Erkanlı, Deniz Usal, Tayfun Bağış

Article info

Successful first trimester intrauterine treatment with alcohol in a case of acardiac twin pregnancy. Perinatal Journal 2014;22(3):SE36 DOI: 10.2399/prn.14.S001084

Author(s) Information

Melih Atahan Güven 1,
Harika Bodur Öztürk2,
Önder Koç3,
Serkan Erkanlı1,
Deniz Usal2,
Tayfun Bağış1

  1. Acıbadem Üniversitesi, Kadın Hastalıkları ve Doğum Anabilim Dalı- İstanbul TR
  2. Acıbadem Kadıköy Hastanesi, Kadın Hastalıkları ve Doğum- İstanbul TR
  3. Memorial Ankara Hastanesi, Kadın Hastalıkları ve Doğum- Ankara TR
Correspondence

Melih Atahan Güven , Acıbadem Üniversitesi, Kadın Hastalıkları ve Doğum Anabilim Dalı- İstanbul TR,

Publication History
Conflicts of Interest

No conflicts declared.

Twin reversed arterial perfusion (TRAP) sequence is a serious condition of monochorionic twin pregnancy. It is an extremely rare anomaly, occurring with a reported incidence of 1 in 35000 deliveries, 1 in 100 monozygotic twins and 1 in 30 monozygotic triplets. This condition is associated high risk of perinatal death of the pump twin due to cardiac failure and polyhidramnios may induce preterm birth.
Several methods have been proposed for intrauterine treatment of acardiac twin pregnancy and selective reduction of the acardiac twin was recently reported to be minimally invasive and effective for intrauterine treatment of acardiac twin pregnancy. First trimester treatment of TRAP sequence is controversies with higher incidence of procedure related complications. We present a case of TRAP sequence that has been managed by intrauterine treatment with alcohol injection at 12 weeks of gestation. Prophylactic intervention at 12 weeks of gestation may be resulted with higher survival rate if the early procedure could prevent fetal loss of pump twin before 16 weeks.
First trimester prophylactic intervention could be recommended patient with TRAP sequence. Alcohol ablation can be performed in medical center unless more sophisticated methods as invasive procedure are not available.
Keywords

Acardiac twin, twin pregnancy, intrauterine intervention

File/Dsecription
Figure 1
Acardiac fetus after delivery