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​Cihat Şen, ​Nicola Volpe

Cecilia Villalain, Daniel Rolnik, M. Mar Gil

Managing Editors
Murat Yayla

Statistics Editor
Resul Arısoy

Article info

OP-001 Fetal branching anomalies of the aortic arch and vascular rings: an experience of a single Italian reference center. Perinatal Journal 2024;32(2024):1 DOI: 10.59215/prn.24.032supp001

Author(s) Information

Antonia Giudicepietro1,
Carmela Morelli 2,
Fiorella Fratta2,
Fortuna Del Gaizo2,
Ludovica Spinelli Barrile2,
Laura Di Pietto2,
Beniamino Tormettino3,
Marialuisa Ricciardiello2,
Maria Giovanna Russo 2

  1. Sant’Anna e San Sebastiano Hospital, Complex Operative Unit - Obstetrics and Gynecology, Caserta, Italy
  2. University of Campania “Luigi Vanvitelli”, Pediatric Cardiology Unit, Department of Translational Medical Sciences, Naples, Italy
  3. Betania Evangelical Hospital, Obstetric Unit, Naples, Italy

Antonia Giudicepietro, Sant’Anna e San Sebastiano Hospital, Complex Operative Unit - Obstetrics and Gynecology, Caserta, Italy, [email protected]

Publication History

Manuscript Received: May 01, 2024

Manuscript Accepted: May 02, 2024

Earlyview Date: May 16, 2024

Publication date: May 18, 2024

Conflicts of Interest

No conflicts declared.

The aim of this study is to analyze concordance between fetal and neonatal diagnosis of branching anomalies of the aortic arch and vascular rings and their clinical outcome in a single Italian reference center
We conducted a retrospective study from January 2021 to December 2023.The prenatal diagnosis was confirmed by postnatal echocardiogram and in cases of suspected vascular rings with a computed tomography (CT)
4711 fetal echocardiography were performed and branching anomalies of the aortic arch or vascular rings were suspected in 103 cases. 62 cases were an incomplete vascular ring aberrant right subclavian artery (ARSA); 1 case was associated with prenatal diagnosis of Tetralogy of Fallot (ToF); 16 cases were isolated right aortic arch (RAA) and 25 were RAA with aberrant left subclavian artery (ALSA) of which 1 case was associated with ToF and persistent left superior vena cava (PLSVC). Only 12 amniocenteses were performed, 75% results with normal karyotype and 25% with chromosomal/genetic abnormalities. In postnatal series, concordance between prenatal diagnoses was 75% for RAA, and 100% for RAA + ALSA. In postnatal, 2 cases of prenatal diagnosis of RAA were associated with ALSA and 2 cases with double aortic arch, but in 1 of these, a CT with conclusive diagnosis of RAA + ALSA was performed
In our series, the most common anomaly was isolated ARSA without cases of dysphagia lusoria in newborns. Our genetic evaluation is suboptimal. In the absence of major congenital heart disease association or karyotype anomalies counseling should be reassuring to parents. 

Vascular rings, fetal echocardiography, prenatal diagnosis, congenital heart disease

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